Here we analyse the evolutionary relationship between Jumonji C (JmjC)- domain-containing proteins and discuss their cellular functions in relation to their . Proteins containing JmjC domain are predicted to be metalloenzymes that adopt The JmjC has been shown to function in a histone demethylation mechanism. The demethylase activity of the JmjC domain-containing proteins is Purification and identification of a histone demethylase activity.a, Histone.
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Systems used to automatically annotate proteins with high accuracy:. An item s and click on “Add to basket” to create your own collection here entries max. Manual assertion inferred from sequence similarity to i. Manual assertion according to rules i. Manual assertion based on experiment in i. This entry has 2 described isoforms and 1 potential isoform that is computationally mapped.
Histone demethylation by a family of JmjC domain-containing proteins.
Show all Align All. This isoform has been chosen as the ‘canonical’ sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. The sequence of this isoform differs from the canonical sequence as follows: You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Your basket is currently empty. JmjC domain-containing histone demethylation protein 1. Reviewed – Annotation score: Select a section on the left to see content. Has a role in regulating lifespan.
Search chemical reactions in Rhea for this molecule. See the description of this molecule in ChEBI. See the description of this reaction in Rhea. N 6N 6 -dimethyl- L -lysine residue.
This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level. Bgee i WBGene Expressed in 5 organ shighest expression level in multi-cellular organism. Several domains are described in this subsection.
Belongs to the JHDM1 histone demethylase family. Additionally, this section gives relevant information on each alternative protein isoform. Align Add to basket Added to basket This entry has 2 described isoforms and 1 potential isoform that is computationally mapped.
Emerging Roles of JmjC Domain-Containing Proteins.
Show all Align All Isoform a identifier: No experimental confirmation available. It is useful for tracking sequence updates. The algorithm is described in the ISO standard. JmjC domain-containing histone deme These are stable identifiers and should be used to cite UniProtKB entries. Q95Q98 Secondary accession number s: March 7, Last sequence update: March 1, Last modified: December 5, This is version of the entry and version 2 of the sequence. National Institutes of Health.
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Priority is given to the annotation of physiological ligands. Chromatin regulatorDioxygenaseOxidoreductase. TranscriptionTranscription regulation. Reactome – a knowledgebase of biological pathways and processes More JmjC domain-containing histone demethylation protein 1 EC: Four distinct tokens exist: It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.
Encyclopedia of Proteome Dynamics More PaxDb, a database of protein abundance averages across all three domains of life More WBGene Expressed in 5 organ shighest expression level in multi-cellular organism.
Database of comparative protein structure models More Non-supervised Orthologous Groups More Eukaryotic Ortholog Groups More Database of Orthologous Groups More Integrated resource of protein families, domains and functional sites More The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.
The information stored in this subsection is used to automatically construct alternative protein sequence s for display.
Missing in isoform b. Select the link destinations: EMBL nucleotide sequence database More Kyoto Encyclopedia of Genes and Genomes More UCSC genome browser More Comparative Toxicogenomics Database More ProtoNet; Automatic hierarchical classification of proteins More Q95Q98 Primary citable accession number: This is version of the entry and version 2 of the sequence.